Core Services

Patient sourcing, ethical consent, tissue processing and storage

iPSC derivation for disease modelling and phenotype validation

Companion assays for assessing disease penetrance & phenotype

Differentiation of iPSCs to specific brain cell types

3D Neurosphere and Blood-Brain Barrier culture and analysis

Gene editing of iPSCs: gene knockout/knock-in, SNPs, INDELs etc

Co-culture of specific iPSC-derived cell types

High content/throughput screening for drug toxicity, efficacy and potency

Omics analysis for network modelling, SNP discovery and differential gene expression

Patient stratification methods, analysis & cohort creation